Xiaohua Gao Selected Research

bardoxolone methyl

12/2015	CDDO-Me inhibits tumor growth and prevents recurrence of pancreatic ductal adenocarcinoma.
5/2014	Induction of Apoptosis in Pancreatic Cancer Cells by CDDO-Me Involves Repression of Telomerase through Epigenetic Pathways.
3/2013	Inhibition of telomerase activity by oleanane triterpenoid CDDO-Me in pancreatic cancer cells is ROS-dependent.
1/2013	ROS mediate proapoptotic and antisurvival activity of oleanane triterpenoid CDDO-Me in ovarian cancer cells.
12/2012	Telomerase reverse transcriptase (TERT) is a therapeutic target of oleanane triterpenoid CDDO-Me in prostate cancer.
6/2012	Inhibition of cell proliferation and induction of apoptosis by oleanane triterpenoid (CDDO-Me) in pancreatic cancer cells is associated with the suppression of hTERT gene expression and its telomerase activity.
1/2012	Oleanane triterpenoid CDDO-Me inhibits Akt activity without affecting PDK1 kinase or PP2A phosphatase activity in cancer cells.
1/2012	Inhibition of cell proliferation and induction of apoptosis by CDDO-Me in pancreatic cancer cells is ROS-dependent.
11/2011	Synthetic oleanane triterpenoid, CDDO-Me, induces apoptosis in ovarian cancer cells by inhibiting prosurvival AKT/NF-κB/mTOR signaling.
1/2011	Prevention of Prostate Cancer with Oleanane Synthetic Triterpenoid CDDO-Me in the TRAMP Mouse Model of Prostate Cancer.

For more, sign up at right for free...

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.

Realize the full power of the drug-disease research graph!

Xiaohua Gao Research Topics

Disease

37	Neoplasms (Cancer) 10/2021 - 07/2002
19	Prostatic Neoplasms (Prostate Cancer) 11/2016 - 01/2003
10	Adenocarcinoma 11/2022 - 01/2008
7	Pancreatic Neoplasms (Pancreatic Cancer) 05/2014 - 09/2007
6	Leiomyoma (Uterine Fibroids) 01/2016 - 07/2010
5	Carcinoma (Carcinomatosis) 11/2016 - 12/2011
4	Leukemia 09/2007 - 07/2002
3	Neoplasm Metastasis (Metastasis) 11/2018 - 01/2011
3	Ovarian Neoplasms (Ovarian Cancer) 01/2014 - 11/2011
3	Wounds and Injuries (Trauma) 06/2008 - 07/2006
3	Myeloid Leukemia (Leukemia, Myelocytic) 01/2006 - 07/2002
2	Breast Neoplasms (Breast Cancer) 01/2021 - 09/2016
2	Body Weight (Weight, Body) 09/2012 - 12/2003
2	Colorectal Neoplasms (Colorectal Cancer) 01/2011 - 03/2010
1	Spinal Cord Injuries (Spinal Cord Injury) 01/2022
1	Weight Loss (Weight Reduction) 01/2022
1	Atopic Dermatitis (Atopic Eczema) 11/2021
1	Hypertension (High Blood Pressure) 10/2021
1	Acute Coronary Syndrome 01/2021
1	Acute Lung Injury 10/2020
1	Hemorrhagic Shock 10/2020
1	Hemorrhage 10/2020
1	Lung Injury 10/2020
1	Fibrosarcoma 01/2019
1	Adenocarcinoma of Lung 11/2018

Drug/Important Bio-Agent (IBA)

21	TriterpenesIBA 07/2016 - 09/2007
18	bardoxolone methylIBA 12/2015 - 09/2007
14	oleananeIBA 05/2014 - 01/2008
11	NF-kappa B (NF-kB)IBA 11/2016 - 07/2004
9	Proteins (Proteins, Gene)FDA Link 01/2021 - 09/2007
7	Hormones (Hormone)IBA 11/2016 - 01/2005
7	celastrol methyl esterIBA 07/2016 - 11/2013
7	Antineoplastic Agents (Antineoplastics)IBA 07/2015 - 01/2005
7	Oleanolic AcidIBA 03/2013 - 09/2007
7	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 01/2008 - 01/2003
7	CurcuminIBA 01/2008 - 01/2003
6	Telomerase (Telomerase Reverse Transcriptase)IBA 07/2015 - 06/2012
6	LigandsIBA 01/2008 - 01/2003
5	bardoxoloneIBA 11/2011 - 09/2007
4	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2013 - 02/2010
4	Phosphotransferases (Kinase)IBA 01/2012 - 01/2007
4	AcidsIBA 05/2011 - 09/2007
4	Cytochromes c (Cytochrome c)IBA 09/2007 - 01/2003
3	Histones (Histone)IBA 10/2020 - 05/2014
3	Transcription Factors (Transcription Factor)IBA 01/2019 - 01/2007
3	SurvivinIBA 10/2014 - 05/2011
3	fenvalerateIBA 10/2012 - 07/2010
3	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 01/2012 - 12/2006
3	EstersIBA 01/2011 - 09/2007
3	CollagenIBA 07/2010 - 07/2006
2	Pharmaceutical PreparationsIBA 01/2022 - 01/2020
2	IronIBA 10/2021 - 07/2006
2	RNA (Ribonucleic Acid)IBA 01/2021 - 11/2018
2	MicroRNAs (MicroRNA)IBA 01/2019 - 11/2018
2	MycotoxinsIBA 11/2016 - 09/2016
2	Estrogen Receptor alphaIBA 01/2016 - 01/2012
2	Estrogen ReceptorsIBA 04/2015 - 10/2012
2	Estrogens (Estrogen)FDA Link 04/2015 - 01/2012
2	UbiquitinIBA 10/2014 - 11/2013
2	Poly(ADP-ribose) Polymerases (Poly ADP Ribose Polymerase)IBA 01/2014 - 11/2011
2	Annexin A5IBA 01/2014 - 11/2011
2	AntioxidantsIBA 01/2011 - 01/2007
2	1- (2- cyano- 3,12- dioxooleana- 1,9- dien- 28- oyl) imidazoleIBA 03/2010 - 09/2007
2	imidazoleIBA 03/2010 - 09/2007
2	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 06/2008 - 12/2006
2	Epidermal Growth Factor (EGF)IBA 06/2008 - 12/2006
2	FITC-annexin A5IBA 09/2007 - 09/2007
2	CytokinesIBA 12/2006 - 01/2006
2	TNF-Related Apoptosis-Inducing LigandIBA 01/2005 - 01/2005
2	ResveratrolIBA 12/2003 - 07/2002
1	Glutamine (L-Glutamine)FDA Link 11/2022
1	1,3-dipropyl-8-cyclopentylxanthineIBA 01/2022
1	NanoconjugatesIBA 01/2022
1	Vitamin D FDA LinkGeneric 11/2021
1	25-hydroxyvitamin DIBA 11/2021
1	Trichloroethylene (Trichloroethene)IBA 10/2021
1	HomocysteineIBA 01/2021
1	Phenobarbital (Luminal)FDA Link 01/2021
1	Biomarkers (Surrogate Marker)IBA 01/2021
1	Vorinostat FDA Link 10/2020
1	Lactic Acid (Lactate)FDA LinkGeneric 10/2020
1	Therapeutic UsesIBA 10/2020
1	salicylhydroxamic acid (SHAM)IBA 10/2020
1	Insulin (Novolin)FDA Link 01/2019
1	arseniteIBA 01/2019
1	SmokeIBA 11/2018
1	ThioredoxinsIBA 11/2018
1	muconomycin AIBA 11/2016
1	trichotheceneIBA 09/2016
1	EpitopesIBA 04/2016
1	Phytoestrogens (Phytoestrogen)IBA 01/2016
1	Mitogen-Activated Protein KinasesIBA 01/2016
1	GenisteinIBA 01/2016
1	CadmiumIBA 04/2015
1	leukotriene D4 receptor (cysteinyl leukotriene receptor)IBA 01/2015

Therapy/Procedure

6	Therapeutics 05/2014 - 01/2005
4	Chemoprevention 12/2011 - 01/2003
3	Immunotherapy 01/2005 - 01/2003
2	Cell- and Tissue-Based Therapy (Cell Therapy) 06/2008 - 07/2006
1	Resuscitation 10/2020